diff --git a/stacks/pinot-noir-gcc13/packages_stack.yaml b/stacks/pinot-noir-gcc13/packages_stack.yaml
index fa5a6509ae775a84738a4568d7631415466c3312..05d4d1047fe2c16556bcecf92ff9184a19b4c754 100644
--- a/stacks/pinot-noir-gcc13/packages_stack.yaml
+++ b/stacks/pinot-noir-gcc13/packages_stack.yaml
@@ -232,6 +232,9 @@ packages:
   py-pandas:
     prefer: ['@2.2.1']
 
+  py-pysam:
+    prefer: ['@0.22.1']
+
   # https://github.com/tensorflow/tensorflow/issues/63360#issuecomment-2142735122
   # MKL support seams not maintained
   py-tensorflow:
@@ -265,6 +268,9 @@ packages:
     require:
     - spec: '^arpack-ng +mpi'
 
+  spades:
+    require: ['~ipo']
+
   suite-sparse:
     require:
       - '+graphblas'